A Method for Gene-Based Pathway Analysis Using Genomewide Association Study Summary Statistics Reveals Nine New Type 1 Diabetes Associations

Pathway analysis can complement point-wise single nucleotide polymorphism (SNP) analysis in exploring genomewide association study (GWAS) data to identify specific disease-associated genes that can be candidate causal genes. We propose a straightforward methodology that can be used for conducting a...

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Vydáno v:Genet Epidemiol
Hlavní autoři: Evangelou, Marina, Smyth, Deborah J, Fortune, Mary D, Burren, Oliver S, Walker, Neil M, Guo, Hui, Onengut-Gumuscu, Suna, Chen, Wei-Min, Concannon, Patrick, Rich, Stephen S, Todd, John A, Wallace, Chris
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2014
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258092/
https://ncbi.nlm.nih.gov/pubmed/25371288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21853
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