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Alterations in microRNA-124 and AMPA receptors contribute to social behavioral deficits in frontotemporal dementia

Many neurodegenerative diseases, such as frontotemporal dementia (FTD), are associated with behavioral deficits, but the anatomical and molecular bases remain poorly understood. Here we show that forebrain-specific expression of FTD-associated mutant CHMP2B causes several age-dependent neurodegenera...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Med
Egile Nagusiak: Gascon, Eduardo, Lynch, Kelleen, Ruan, Hongyu, Almeida, Sandra, Verheyden, Jamie, Seeley, William W., Dickson, Dennis W., Petrucelli, Leonard, Sun, Danqiong, Jiao, Jian, Zhou, Hongru, Jakovcevski, Mira, Akbarian, Schahram, Yao, Wei-Dong, Gao, Fen-Biao
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4257887/
https://ncbi.nlm.nih.gov/pubmed/25401692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3717
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