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Altered phenotype and function of natural killer cells expressing the major histocompatibility complex receptor Ly-49 in mice transgenic for its ligand.

The Ly-49 molecule has been shown to interact with major histocompatibility complex (MHC) class I molecules, and the lytic function of Ly-49+ natural killer (NK) cells from C57BL/6 (H-2b) mice is inhibited by the recognition of H-2Dd on tumor target cells. Introduction of a Ly-49 ligand, H-2Dd, into...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Olsson, M Y, Kärre, K, Sentman, C L
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42577/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7878033/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.5.1649
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