Accounting for eXentricities: Analysis of the X Chromosome in GWAS Reveals X-Linked Genes Implicated in Autoimmune Diseases

Many complex human diseases are highly sexually dimorphic, suggesting a potential contribution of the X chromosome to disease risk. However, the X chromosome has been neglected or incorrectly analyzed in most genome-wide association studies (GWAS). We present tailored analytical methods and software...

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Publicat a:PLoS One
Autors principals: Chang, Diana, Gao, Feng, Slavney, Andrea, Ma, Li, Waldman, Yedael Y., Sams, Aaron J., Billing-Ross, Paul, Madar, Aviv, Spritz, Richard, Keinan, Alon
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4257614/
https://ncbi.nlm.nih.gov/pubmed/25479423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113684
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