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Residual Endotoxin Contaminations in Recombinant Proteins Are Sufficient to Activate Human CD1c(+) Dendritic Cells

Many commercially available recombinant proteins are produced in Escherichia coli, and most suppliers guarantee contamination levels of less than 1 endotoxin unit (EU). When we analysed commercially available proteins for their endotoxin content, we found contamination levels in the same range as ge...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Schwarz, Harald, Schmittner, Maria, Duschl, Albert, Horejs-Hoeck, Jutta
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4257590/
https://ncbi.nlm.nih.gov/pubmed/25478795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113840
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