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The p150Glued component of the dynactin complex binds to both microtubules and the actin-related protein centractin (Arp-1).

p150Glued was first identified as a polypeptide that copurifies with cytoplasmic dynein, the minus-end-directed microtubule-based motor protein, and has more recently been shown to be present as a member of the oligomeric dynactin complex, which includes the actin-related protein centractin (Arp-1)....

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Bibliographic Details
Main Authors: Waterman-Storer, C M, Karki, S, Holzbaur, E L
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC42574/
https://ncbi.nlm.nih.gov/pubmed/7878030
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