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The sleep–wake cycle and Alzheimer’s disease: what do we know?

Sleep–wake disturbances are a highly prevalent and often disabling feature of Alzheimer’s disease (AD). A cardinal feature of AD includes the formation of amyloid plaques, associated with the extracellular accumulation of the amyloid-β (Aβ) peptide. Evidence from animal and human studies suggests th...

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Detalhes bibliográficos
Publicado no:Neurodegener Dis Manag
Main Authors: Lim, Miranda M., Gerstner, Jason R., Holtzman, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4257134/
https://ncbi.nlm.nih.gov/pubmed/25405649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nmt.14.33
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