Design, Assessment, and in vivo Evaluation of a Computational Model Illustrating the Role of CAV1 in CD4(+) T-lymphocytes

Caveolin-1 (CAV1) is a vital scaffold protein heterogeneously expressed in both healthy and malignant tissue. We focus on the role of CAV1 when overexpressed in T-cell leukemia. Previously, we have shown that CAV1 is involved in cell-to-cell communication, cellular proliferation, and immune synapse...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Conroy, Brittany D., Herek, Tyler A., Shew, Timothy D., Latner, Matthew, Larson, Joshua J., Allen, Laura, Davis, Paul H., Helikar, Tomáš, Cutucache, Christine E.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4257089/
https://ncbi.nlm.nih.gov/pubmed/25538703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00599
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