Recombinant Lactobacillus plantarum expressing and secreting heterologous oxalate decarboxylase prevents renal calcium oxalate stone deposition in experimental rats

BACKGROUND: Calcium oxalate (CaOx) is the major constituent of about 75% of all urinary stone and the secondary hyperoxaluria is a primary risk factor. Current treatment options for the patients with hyperoxaluria and CaOx stone diseases are limited. Oxalate degrading bacteria might have beneficial...

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Foilsithe in:J Biomed Sci
Main Authors: Sasikumar, Ponnusamy, Gomathi, Sivasamy, Anbazhagan, Kolandaswamy, Abhishek, Albert, Paul, Eldho, Vasudevan, Varadaraj, Sasikumar, Sundaresan, Selvam, Govindan Sadasivam
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2014
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256919/
https://ncbi.nlm.nih.gov/pubmed/25175550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-014-0086-y
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