Interleukin-5–producing group 2 innate lymphoid cells control eosinophilia induced by interleukin-2 therapy

Interleukin (IL)-2 promotes regulatory T-cell development and function, and treatment with IL-2 is being tested as therapy for some autoimmune diseases. However, patients receiving IL-2 treatment also experience eosinophilia due to an unknown mechanism. Here, we show that patients receiving low-dose...

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Опубликовано в: :Blood
Главные авторы: Van Gool, Frédéric, Molofsky, Ari B., Morar, Malika M., Rosenzwajg, Michelle, Liang, Hong-Erh, Klatzmann, David, Locksley, Richard M., Bluestone, Jeffrey A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2014
Предметы:
Immunobiology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256909/
https://ncbi.nlm.nih.gov/pubmed/25323825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-07-587493
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