Neutralizing antibodies and fatigue as predictors of low response to interferon-beta treatment in patients with multiple sclerosis

BACKGROUND: The clinical impact of neutralizing antibodies against interferon-beta (NAb) is controversial. Their presence can lead to a decrease in interferon-beta (IFNβ) efficacy. Fatigue reported in patients with multiple sclerosis (MS) may be associated with an unfavorable clinical course. We con...

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Publicado en:BMC Neurol
Autores principales: Manceau, Philippe, Latarche, Clotilde, Pittion, Sophie, Edan, Gilles, de Sèze, Jérôme, Massart, Catherine, Debouverie, Marc
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256902/
https://ncbi.nlm.nih.gov/pubmed/25433670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12883-014-0215-y
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