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Developmental Defects in a Caenorhabditis elegans Model for Type III Galactosemia
Type III galactosemia is a metabolic disorder caused by reduced activity of UDP-galactose-4-epimerase, which participates in galactose metabolism and the generation of various UDP-sugar species. We characterized gale-1 in Caenorhabditis elegans and found that a complete loss-of-function mutation is...
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Publicado no: | Genetics |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Genetics Society of America
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4256771/ https://ncbi.nlm.nih.gov/pubmed/25298520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.170084 |
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