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Increased Meiotic Crossovers and Reduced Genome Stability in Absence of Schizosaccharomyces pombe Rad16 (XPF)

Schizosaccharomyces pombe Rad16 is the ortholog of the XPF structure-specific endonuclease, which is required for nucleotide excision repair and implicated in the single strand annealing mechanism of recombination. We show that Rad16 is important for proper completion of meiosis. In its absence, cel...

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Detalles Bibliográficos
Publicado en:Genetics
Main Authors: Mastro, Tara L., Forsburg, Susan L.
Formato: Artigo
Idioma:Inglês
Publicado: Genetics Society of America 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256765/
https://ncbi.nlm.nih.gov/pubmed/25293972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.171355
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