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Biased Estimates of Diminishing-Returns Epistasis? Empirical Evidence Revisited
Empirical evidence for diminishing fitness returns of beneficial mutations supports Fisher’s geometric model. We show that a similar pattern emerges through the phenomenon of regression to the mean and that few studies correct for it. Although biases are often small, regression to the mean has overe...
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| Publicado no: | Genetics |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4256761/ https://ncbi.nlm.nih.gov/pubmed/25313131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.169870 |
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