Oligosaccharyltransferase Subunits Bind Polypeptide Substrate to Locally Enhance N-glycosylation

Oligosaccharyltransferase is a multiprotein complex that catalyzes asparagine-linked glycosylation of diverse proteins. Using yeast genetics and glycoproteomics, we found that transient interactions between nascent polypeptide and Ost3p/Ost6p, homologous subunits of oligosaccharyltransferase, were a...

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Bibliographic Details
Published in:Mol Cell Proteomics
Main Authors: Jamaluddin, M. Fairuz B., Bailey, Ulla-Maja, Schulz, Benjamin L.
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2014
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256483/
https://ncbi.nlm.nih.gov/pubmed/25118247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M114.041178
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