SV40 Utilizes ATM Kinase Activity to Prevent Non-homologous End Joining of Broken Viral DNA Replication Products

Simian virus 40 (SV40) and cellular DNA replication rely on host ATM and ATR DNA damage signaling kinases to facilitate DNA repair and elicit cell cycle arrest following DNA damage. During SV40 DNA replication, ATM kinase activity prevents concatemerization of the viral genome whereas ATR activity p...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS Pathog
Päätekijät: Sowd, Gregory A., Mody, Dviti, Eggold, Joshua, Cortez, David, Friedman, Katherine L., Fanning, Ellen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2014
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256475/
https://ncbi.nlm.nih.gov/pubmed/25474690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004536
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