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A Liquid Chromatography-Mass Spectrometry-based Approach to Characterize the Substrate Specificity of Mammalian Heparanase

Extracellular heparanase activity releases growth factors and angiogenic factors from heparan sulfate (HS) storage sites and alters the integrity of the extracellular matrix. These activities lead to a loss of normal cell matrix adherent junctions and correlate with invasive cellular phenotypes. Ele...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Mao, Yang, Huang, Yu, Buczek-Thomas, Jo Ann, Ethen, Cheryl M., Nugent, Matthew A., Wu, Zhengliang L., Zaia, Joseph
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256347/
https://ncbi.nlm.nih.gov/pubmed/25336655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.589630
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