Structural Insights into the C1q Domain of Caprin-2 in Canonical Wnt Signaling

Previously, we have identified Caprin-2 as a new regulator in canonical Wnt signaling through a mechanism of facilitating LRP5/6 phosphorylation; moreover, we found that its C-terminal C1q-related domain (Cap2_CRD) is required for this process. Here, we determined the crystal structures of Cap2_CRD...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Miao, Haofei, Jia, Yingying, Xie, Sichun, Wang, Xin, Zhao, Jianfei, Chu, Youjun, Zhou, Zhilei, Shi, Zhubing, Song, Xiaomin, Li, Lin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256344/
https://ncbi.nlm.nih.gov/pubmed/25331957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.591636
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge