Cardiac Function Is Regulated by B56α-mediated Targeting of Protein Phosphatase 2A (PP2A) to Contractile Relevant Substrates

Dephosphorylation of important myocardial proteins is regulated by protein phosphatase 2A (PP2A), representing a heterotrimer that is comprised of catalytic, scaffolding, and regulatory (B) subunits. There is a multitude of B subunit family members directing the PP2A holoenzyme to different myocellu...

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Vydáno v:J Biol Chem
Hlavní autoři: Kirchhefer, Uwe, Brekle, Christiane, Eskandar, John, Isensee, Gunnar, Kučerová, Dana, Müller, Frank U., Pinet, Florence, Schulte, Jan S., Seidl, Matthias D., Boknik, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256322/
https://ncbi.nlm.nih.gov/pubmed/25320082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.598938
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