Therapeutic Administration of Recombinant Paracoccin Confers Protection against Paracoccidioides brasiliensis Infection: Involvement of TLRs

BACKGROUND: Paracoccin (PCN) is an N-acetylglucosamine-binding lectin from the human pathogenic fungus Paracoccidioides brasiliensis. Recombinant PCN (rPCN) induces a T helper (Th) 1 immune response when prophylactically administered to BALB/c mice, protecting them against subsequent challenge with...

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Bibliographic Details
Published in:PLoS Negl Trop Dis
Main Authors: Alegre-Maller, Ana Claudia Paiva, Mendonça, Flávia Costa, da Silva, Thiago Aparecido, Oliveira, Aline Ferreira, Freitas, Mateus Silveira, Hanna, Ebert Seixas, Almeida, Igor C., Gay, Nicholas J., Roque-Barreira, Maria Cristina
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256291/
https://ncbi.nlm.nih.gov/pubmed/25474158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003317
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