MiR-143 and MiR-145 Regulate IGF1R to Suppress Cell Proliferation in Colorectal Cancer

Insulin-like growth factor 1 receptor (IGF1R) is a transmembrane receptor that is activated by insulin-like growth factor 1 (IGF-1) and by a related hormone called IGF-2. It belongs to the large class of tyrosine kinase receptors and plays an important role in colorectal cancer etiology and progress...

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Bibliographic Details
Published in:PLoS One
Main Authors: Su, Jiaojiao, Liang, Hongwei, Yao, Weiyan, Wang, Nan, Zhang, Suyang, Yan, Xin, Feng, Hui, Pang, Wenjing, Wang, Yanbo, Wang, Xueliang, Fu, Zhen, Liu, Yanqing, Zhao, Chihao, Zhang, Junfeng, Zhang, Chen-Yu, Zen, Ke, Chen, Xi, Wang, Yalei
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256231/
https://ncbi.nlm.nih.gov/pubmed/25474488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114420
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