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The impact of exposure-biased sampling designs on detection of gene-environment interactions in case-control studies with potential exposure misclassification

BACKGROUND: With limited funding and biological specimen availability, choosing an optimal sampling design to maximize power for detecting gene-by-environment (G-E) interactions is critical. Enriched sampling is often used to select subjects with rare exposures for genotyping to enhance power for te...

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Publicado en:Eur J Epidemiol
Autores principales: Stenzel, Stephanie L., Ahn, Jaeil, Boonstra, Philip S., Gruber, Stephen B., Mukherjee, Bhramar
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256150/
https://ncbi.nlm.nih.gov/pubmed/24894824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10654-014-9908-1
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