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Lycopene attenuated hepatic tumorigenesis via differential mechanisms depending on carotenoid cleavage enzyme in mice

Obesity is associated with increased liver cancer risks and mortality. We recently showed that apo-10’-lycopenoic acid, a lycopene metabolite generated by beta-carotene-9’,10’-oxygenase (BCO2), inhibited carcinogen-initiated, high-fat diet (HFD)-promoted liver inflammation and hepatic tumorigenesis...

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Detalhes bibliográficos
Publicado no:Cancer Prev Res (Phila)
Main Authors: Ip, Blanche C., Liu, Chun, Ausman, Lynne M., von Lintig, Johannes, Wang, Xiang-Dong
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256117/
https://ncbi.nlm.nih.gov/pubmed/25293877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-14-0154
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