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Tri-modal regulation of cardiac muscle relaxation; intracellular calcium decline, thin filament deactivation, and cross-bridge cycling kinetics

Cardiac muscle relaxation is an essential step in the cardiac cycle. Even when the contraction of the heart is normal and forceful, a relaxation phase that is too slow will limit proper filling of the ventricles. Relaxation is too often thought of as a mere passive process that follows contraction....

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Foilsithe in:Biophys Rev
Main Authors: Biesiadecki, Brandon J., Davis, Jonathan P., Ziolo, Mark T., Janssen, Paul M. L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Springer Berlin Heidelberg 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255972/
https://ncbi.nlm.nih.gov/pubmed/28510030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-014-0143-5
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