A multicentre phase III randomised controlled single-masked clinical trial evaluating the clinical efficacy and safety of light-masks at preventing dark-adaptation in the treatment of early diabetic macular oedema (CLEOPATRA): study protocol for a randomised controlled trial

BACKGROUND: This study will evaluate hypoxia, as a novel concept in the pathogenesis of diabetic macular oedema (DMO). As the oxygen demand of the eye is maximum during dark-adaptation, we hypothesize that wearing light-masks during sleep will cause regression and prevent the development and progres...

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Detalhes bibliográficos
Publicado no:Trials
Main Authors: Sivaprasad, Sobha, Arden, Geoffrey, Prevost, A Toby, Crosby-Nwaobi, Roxanne, Holmes, Helen, Kelly, Joanna, Murphy, Caroline, Rubin, Gary, Vasconcelos, Joanna, Hykin, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Study Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255925/
https://ncbi.nlm.nih.gov/pubmed/25417120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6215-15-458
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