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Sox5 is a DNA binding co-factor for BMP R-Smads that directs target specificity during patterning of the early ectoderm

The SoxD factor, Sox5, is expressed in ectodermal cells at times and places where BMP signaling is active, including the cells of the animal hemisphere at blastula stages, and the neural plate border (NPB) and neural crest (NC) at neurula stages. Sox5 is required for proper ectoderm development, and...

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Dettagli Bibliografici
Pubblicato in:Dev Cell
Autori principali: Nordin, Kara, LaBonne, Carole
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255363/
https://ncbi.nlm.nih.gov/pubmed/25453832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.10.003
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