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Epigenetic clustering of lung adenocarcinomas based on DNA methylation profiles in adjacent lung tissue: Its correlation with smoking history and chronic obstructive pulmonary disease

The aim of this study was to clarify the significance of DNA methylation alterations during lung carcinogenesis. Infinium assay was performed using 139 paired samples of non-cancerous lung tissue (N) and tumorous tissue (T) from a learning cohort of patients with lung adenocarcinomas (LADCs). Fifty...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Sato, Takashi, Arai, Eri, Kohno, Takashi, Takahashi, Yoriko, Miyata, Sayaka, Tsuta, Koji, Watanabe, Shun-ichi, Soejima, Kenzo, Betsuyaku, Tomoko, Kanai, Yae
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255314/
https://ncbi.nlm.nih.gov/pubmed/24921089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.28684
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