The Melanocortin-4 Receptor is Expressed in Enteroendocrine L Cells and Regulates the Release of Peptide YY and Glucagon-Like Peptide 1 In Vivo

The melanocortin-4 receptor (MC4R) is expressed in the brainstem and vagal afferent nerves, and regulates a number of aspects of gastrointestinal function. Here we show that the receptor is also diffusely expressed in cells of the gastrointestinal system, from stomach to descending colon. Furthermor...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Panaro, Brandon L., Tough, Iain R., Engelstoft, Maja Storm, Matthews, Robert T., Digby, Gregory J., Møller, Cathrine Laustrup, Svendsen, Berit, Gribble, Fiona, Reimann, Frank, Holst, Jens J., Holst, Birgitte, Schwartz, Thue W., Cox, Helen M., Cone, Roger D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255280/
https://ncbi.nlm.nih.gov/pubmed/25453189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2014.10.004
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