Dynamics and Interaction of Interleukin-4 Receptor Subunits in Living Cells

It has long been established that dimerization of Interleukin-4 receptor (IL-4R) subunits is a pivotal step for JAK/STAT signal transduction. However, ligand-induced complex formation at the surface of living cells has been challenging to observe. Here we report an experimental assay employing trisN...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Gandhi, Hetvi, Worch, Remigiusz, Kurgonaite, Kristina, Hintersteiner, Martin, Schwille, Petra, Bökel, Christian, Weidemann, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2014
Assuntos:
Cell Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255262/
https://ncbi.nlm.nih.gov/pubmed/25468331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.07.077
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