A role for the Parkinson’s disease protein DJ-1 as a chaperone and antioxidant in the anhydrobiotic nematode Panagrolaimus superbus

Mutations in the human DJ-1/PARK7 gene are associated with familial Parkinson’s disease. DJ-1 belongs to a large, functionally diverse family with homologues in all biological kingdoms. Several activities have been demonstrated for DJ-1: an antioxidant protein, a redox-regulated molecular chaperone...

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Publicat a:Cell Stress Chaperones
Autors principals: Culleton, Bridget A., Lall, Patrick, Kinsella, Gemma K., Doyle, Sean, McCaffrey, John, Fitzpatrick, David A., Burnell, Ann M.
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2014
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Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255249/
https://ncbi.nlm.nih.gov/pubmed/25318690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-014-0531-6
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