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Leptin-inhibited PBN neurons enhance counter-regulatory responses to hypoglycemia in negative energy balance

Hypoglycemia initiates the counter regulatory response (CRR), in which the sympathetic nervous system, glucagon, and glucocorticoids restore glucose to appropriate concentrations. During starvation, low leptin restrains energy utilization, enhancing long-term survival. To ensure short-term survival...

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Detalhes bibliográficos
Publicado no:Nat Neurosci
Main Authors: Flak, Jonathan N., Patterson, Christa M., Garfield, Alastair S., D’Agostino, Giuseppe, Goforth, Paulette B., Sutton, Amy K., Malec, Paige A., Wong, Jenny-Marie T., Germani, Mark, Jones, Justin C., Rajala, Michael, Satin, Leslie, Rhodes, Christopher J., Olson, David P., Kennedy, Robert T., Heisler, Lora K., Myers, Martin G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255234/
https://ncbi.nlm.nih.gov/pubmed/25383904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3861
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