A Comprehensive Evaluation of the Efficacy of Leading Oxime Therapies in Guinea Pigs Exposed to Organophosphorus Chemical Warfare Agents or Pesticides

The currently fielded pre-hospital therapeutic regimen for the treatment of organophosphorus (OP) poisoning in the United States (U.S.) is the administration of atropine in combination with an oxime antidote (2-PAM Cl) to reactivate inhibited acetylcholinesterase (AChE). Depending on clinical sympto...

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Gepubliceerd in:Toxicol Appl Pharmacol
Hoofdauteurs: Wilhelm, Christina M., Snider, Thomas H., Babin, Michael C., Jett, David A., Platoff, Gennady E., Yeung, David T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255143/
https://ncbi.nlm.nih.gov/pubmed/25448441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2014.10.009
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