Sulfonylurea Treatment Before Genetic Testing in Neonatal Diabetes: Pros and Cons

CONTEXT: Diabetes in neonates nearly always has a monogenic etiology. Earlier sulfonylurea therapy can improve glycemic control and potential neurodevelopmental outcomes in children with KCNJ11 or ABCC8 mutations, the most common gene causes. OBJECTIVE: Assess the risks and benefits of initiating su...

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Pubblicato in:J Clin Endocrinol Metab
Autori principali: Carmody, David, Bell, Charles D., Hwang, Jessica L., Dickens, Jazzmyne T., Sima, Daniela I., Felipe, Dania L., Zimmer, Carrie A., Davis, Ajuah O., Kotlyarevska, Kateryna, Naylor, Rochelle N., Philipson, Louis H., Greeley, Siri Atma W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2014
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JCEM Online: Advances in Genetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255121/
https://ncbi.nlm.nih.gov/pubmed/25238204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-2494
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