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DMAP1 is an essential regulator of ATM activity and function

The hereditary autosomal recessive disease ataxia telangiectasia (A-T) is caused by mutation in the DNA damage kinase ATM. ATM’s main function is to orchestrate DNA repair, thereby maintaining genomic stability. ATM activity is increased in response to several stimuli, including ionising radiation (...

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Bibliografiska uppgifter
I publikationen:Oncogene
Huvudupphovsmän: Penicud, Kay, Behrens, Axel
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255061/
https://ncbi.nlm.nih.gov/pubmed/23318425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.597
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