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DMAP1 is an essential regulator of ATM activity and function
The hereditary autosomal recessive disease ataxia telangiectasia (A-T) is caused by mutation in the DNA damage kinase ATM. ATM’s main function is to orchestrate DNA repair, thereby maintaining genomic stability. ATM activity is increased in response to several stimuli, including ionising radiation (...
Shranjeno v:
| izdano v: | Oncogene |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4255061/ https://ncbi.nlm.nih.gov/pubmed/23318425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.597 |
| Oznake: |
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