Effects of a myofilament calcium sensitizer on left ventricular systolic and diastolic function in rats with volume overload heart failure

Aortocaval fistula (ACF)-induced volume overload (VO) heart failure (HF) results in progressive left ventricular (LV) dysfunction. Hemodynamic load reversal during pre-HF (4 wk post-ACF; REV) results in rapid structural but delayed functional recovery. This study investigated myocyte and myofilament...

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Publicat a:Am J Physiol Heart Circ Physiol
Autors principals: Wilson, Kristin, Guggilam, Anuradha, West, T. Aaron, Zhang, Xiaojin, Trask, Aaron J., Cismowski, Mary J., de Tombe, Pieter, Sadayappan, Sakthivel, Lucchesi, Pamela A.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2014
Matèries:
Muscle Mechanics and Ventricular Function
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255015/
https://ncbi.nlm.nih.gov/pubmed/25260618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00423.2014
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