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Regulation of Notch 1 signaling in THP-1 cells enhances M(2) macrophage differentiation

Macrophage polarization is emerging as an important area of research for the development of novel therapeutics to treat inflammatory diseases. Within the current study, the role of Notch1R in macrophage differentiation was investigated as well as downstream effects in THP-1 monocytes cultured in “in...

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Veröffentlicht in:Am J Physiol Heart Circ Physiol
Hauptverfasser: Singla, Reetu D., Wang, Jing, Singla, Dinender K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255013/
https://ncbi.nlm.nih.gov/pubmed/25260616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00896.2013
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