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Intermittent hypoxia-induced glucose intolerance is abolished by α-adrenergic blockade or adrenal medullectomy

Obstructive sleep apnea causes intermittent hypoxia (IH) during sleep and is associated with dysregulation of glucose metabolism. We developed a novel model of clinically realistic IH in mice to test the hypothesis that IH causes hyperglycemia, glucose intolerance, and insulin resistance via activat...

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Pubblicato in:Am J Physiol Endocrinol Metab
Autori principali: Jun, Jonathan C., Shin, Mi-Kyung, Devera, Ronald, Yao, Qiaoling, Mesarwi, Omar, Bevans-Fonti, Shannon, Polotsky, Vsevolod Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254988/
https://ncbi.nlm.nih.gov/pubmed/25315697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00373.2014
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