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Diabetic nephropathy is resistant to oral l-arginine or l-citrulline supplementation
Our recent publication showed that pharmacological blockade of arginases confers kidney protection in diabetic nephropathy via a nitric oxide (NO) synthase (NOS)3-dependent mechanism. Arginase competes with endothelial NOS (eNOS) for the common substrate l-arginine. Lack of l-arginine results in red...
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| Publicado no: | Am J Physiol Renal Physiol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4254967/ https://ncbi.nlm.nih.gov/pubmed/25320354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00176.2014 |
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