Mitigation of autophagy ameliorates hepatocellular damage following ischemia-reperfusion injury in murine steatotic liver

Ischemia-reperfusion injury (IRI) is a common clinical consequence of hepatic surgery, cardiogenic shock, and liver transplantation. A steatotic liver is particularly vulnerable to IRI, responding with extensive hepatocellular injury. Autophagy, a lysosomal pathway balancing cell survival and cell d...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: Gupta, Nitika A., Kolachala, Vasantha L., Jiang, Rong, Abramowsky, Carlos, Shenoi, Asha, Kosters, Astrid, Pavuluri, Haritha, Anania, Frank, Kirk, Allan D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Liver and Biliary Tract
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254956/
https://ncbi.nlm.nih.gov/pubmed/25258410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00210.2014
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