Neuroprotectin/protectin D1: endogenous biosynthesis and actions on diabetic macrophages in promoting wound healing and innervation impaired by diabetes

Dysfunction of macrophages (MΦs) in diabetic wounds impairs the healing. MΦs produce anti-inflammatory and pro-resolving neuroprotectin/protectin D1 (NPD1/PD1, 10R,17S-dihydroxy-docosa-4Z,7Z,11E,13E,15Z,19Z-hexaenoic acid); however, little is known about endogenous NPD1 biosynthesis by MΦs and the a...

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Vydáno v:Am J Physiol Cell Physiol
Hlavní autoři: Hong, Song, Tian, Haibin, Lu, Yan, Laborde, James Monroe, Muhale, Filipe A., Wang, Quansheng, Alapure, Bhagwat V., Serhan, Charles N., Bazan, Nicolas G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254953/
https://ncbi.nlm.nih.gov/pubmed/25273880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00270.2014
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