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SelR/MsrB Reverses Mical-mediated Oxidation of Actin to Regulate F-actin Dynamics

Actin's polymerization properties are dramatically altered by oxidation of its conserved methionine (Met)-44 residue. Mediating this effect is a specific oxidation-reduction (Redox) enzyme, Mical, that works with Semaphorin repulsive guidance cues and selectively oxidizes Met-44. We now find th...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Hung, Ruei-Jiun, Spaeth, Christopher S., Yesilyurt, Hunkar Gizem, Terman, Jonathan R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254815/
https://ncbi.nlm.nih.gov/pubmed/24212093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2871
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