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An Improved Optical Tweezers Assay for Measuring the Force Generation of Single Kinesin Molecules

Numerous microtubule-associated molecular motors, including several kinesins and cytoplasmic dynein, produce opposing forces that regulate spindle and chromosome positioning during mitosis. The motility and force generation of these motors are therefore critical to normal cell division, and dysfunct...

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Vydáno v:Methods Mol Biol
Hlavní autoři: Nicholas, Matthew P., Rao, Lu, Gennerich, Arne
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254714/
https://ncbi.nlm.nih.gov/pubmed/24633799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-0329-0_10
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