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Development of Physiologically Based Pharmacokinetic Model (PBPK) of BMP2 in Mice

Bone Morphogenetic protein 2 holds great promise for potential applications in the clinic. It is a potent growth factor for the use in the cervical spine surgery (FDA approved 2002) and has been marketed as “Infuse” for treating open tibial shaft fractures (FDA approved 2004). However, its use is li...

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Bibliografiska uppgifter
I publikationen:Biol Syst Open Access
Huvudupphovsmän: Utturkar, Aditya, Paul, Bikram, Akkiraju, Hemanth, Bonor, Jeremy, Dhurjati, Prasad, Nohe, Anja
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254668/
https://ncbi.nlm.nih.gov/pubmed/25485286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2329-6577.1000123
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