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SRF regulates craniofacial development through selective recruitment of MRTF cofactors by PDGF signaling

Receptor tyrosine kinase signaling is critical for mammalian craniofacial development, but the key downstream transcriptional effectors remain unknown. We demonstrate that SRF is induced by both PDGF and FGF signaling in mouse embryonic palatal mesenchyme cells, and Srf neural crest conditional muta...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Vasudevan, Harish N., Soriano, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254610/
https://ncbi.nlm.nih.gov/pubmed/25453829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.10.005
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