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Reduced affinity of the androgen receptor for 5 alpha-dihydrotestosterone but not methyltrienolone in a form of partial androgen resistance. Studies on cultured genital skin fibroblasts.

We have studied a child with posterior labial fusion, clitoral phallus, female urethra, and a short, blind vagina born to a mother with decreased axillary and pubic hair. Her karyotype is 46,XY. At 2 yr of age, the child's basal level of plasma testosterone was less than 0.35 nM and after human...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Pinsky, L, Kaufman, M, Chudley, A E
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC425458/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3872888/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111829
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