Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen Presenting Cells, Critical for T cell Immunity

It is well understood that antigen-presenting cells (APC) within tumors typically do not maintain cytotoxic T cell (CTL) function, despite engaging them. Across multiple mouse tumor models and human tumor biopsies, we have delineated the intratumoral dendritic-cell (DC) populations as distinct from...

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Detalhes bibliográficos
Publicado no:Cancer Cell
Main Authors: Broz, Miranda, Binnewies, Mikhail, Boldajipour, Bijan, Nelson, Amanda, Pollock, Joshua, Erle, David, Barczak, Andrea, Rosenblum, Michael, Daud, Adil, Barber, Diane, Amigorena, Sebastian, van’t Veer, Laura J., Sperling, Anne, Wolf, Denise, Krummel, Matthew F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254577/
https://ncbi.nlm.nih.gov/pubmed/25446897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2014.09.007
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