Early Retinal Function Deficit without Prominent Morphological Changes in the R6/2 Mouse Model of Huntington’s Disease

Huntington’s disease (HD) is an inherited neurodegenerative disorder that primarily affects the medium-size GABAergic neurons of striatum. The R6/2 mouse line is one of the most widely used animal models of HD. Previously the hallmarks of HD-related pathology have been detected in photoreceptors and...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Ragauskas, Symantas, Leinonen, Henri, Puranen, Jooseppi, Rönkkö, Seppo, Nymark, Soile, Gurevicius, Kestutis, Lipponen, Arto, Kontkanen, Outi, Puoliväli, Jukka, Tanila, Heikki, Kalesnykas, Giedrius
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2014
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254453/
https://ncbi.nlm.nih.gov/pubmed/25469887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113317
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