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From Monoclonal Antibodies to Chimeric Antigen Receptors for the Treatment of Human Malignancies

Monoclonal antibodies (mAbs) and their directly derived cell-based application known as chimeric antigen receptors (CARs) ensue from the need to develop novel therapeutic strategies that retain high anti-tumor activity, but carry reduced toxicity compared to conventional chemo- and radio-therapies....

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Détails bibliographiques
Publié dans:Semin Oncol
Auteurs principaux: Caruana, Ignazio, Diaconu, Iulia, Dotti, Gianpietro
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254449/
https://ncbi.nlm.nih.gov/pubmed/25440610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.seminoncol.2014.08.005
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