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Approaches for establishing the function of regulatory genetic variants involved in disease

The diversity of regulatory genetic variants and their mechanisms of action reflect the complexity and context-specificity of gene regulation. Regulatory variants are important in human disease and defining such variants and establishing mechanism is crucial to the interpretation of disease-associat...

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Detalhes bibliográficos
Publicado no:Genome Med
Autor principal: Knight, Julian Charles
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254439/
https://ncbi.nlm.nih.gov/pubmed/25473428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-014-0092-4
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