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Heterogeneity of glycolysis in cancers and therapeutic opportunities

Upregulated glycolysis, both in normoxic and hypoxic environments, is a nearly universal trait of cancer cells. The enormous difference in glucose metabolism offers a target for therapeutic intervention with a potentially low toxicity profile. The past decade has seen a steep rise in the development...

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Dettagli Bibliografici
Pubblicato in:Biochem Pharmacol
Autori principali: Warmoes, Marc O., Locasale, Jason W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254151/
https://ncbi.nlm.nih.gov/pubmed/25093285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2014.07.019
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